The essential and downstream common proteins of amyotrophic lateral sclerosis: A protein-protein interaction network analysis.

Amyotrophic Lateral Sclerosis (ALS) is a devastative neurodegenerative disease characterized by selective loss of motoneurons. While several breakthroughs have been made in identifying ALS genetic defects, the detailed molecular mechanisms are still unclear. These genetic defects involve in numerous...

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Bibliographic Details
Main Authors: Yimin Mao, Su-Wei Kuo, Le Chen, C J Heckman, M C Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5345759?pdf=render