GHRH-GH-IGF1 axis in pediatric Down syndrome: A systematic review and mini meta-analysis

GHRH-GH-IGF1 axis in pediatric Down syndrome: A systematic review and mini meta-analysis

ObjectiveTo analyze and determine the quality of functioning in different components of GHRH-GH-IGF1 axis in children with Down syndrome (DS).DesignSystematic review and mini meta-analysis of the literature.MethodsA search was performed in PubMed, Embase, Scopus, and PsycINFO through August 2022. El...

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Bibliographic Details
Main Authors: David Shaki, Eli Hershkovitz, Shai Tamam, Arkadi Bollotin, Odeya David, Guy Yalovitsky, Neta Loewenthal, Lior Carmon, Dganit Walker, Alon Haim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pediatrics
Subjects:
growth hormone
Down syndrome
IGF1
neurosecretory dysfunction
bio-inactive GH
hypothalamus
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1132296/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2023.1132296/full

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