Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a cohort of 194 healthy older adults ages 50–89, we used...

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Hlavní autoři: Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2024-03-01
Edice:Frontiers in Aging Neuroscience
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full