Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a cohort of 194 healthy older adults ages 50–89, we used...

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Détails bibliographiques
Auteurs principaux: Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2024-03-01
Collection:Frontiers in Aging Neuroscience
Sujets:
regional white matter hyperintensity volume
hippocampal volume
brain aging
subjective memory complaints
scaled subprofile model
multivariate analyses
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

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