Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a cohort of 194 healthy older adults ages 50–89, we used...

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Dettagli Bibliografici
Autori principali: Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Natura: Articolo
Lingua:English
Pubblicazione: Frontiers Media S.A. 2024-03-01
Serie:Frontiers in Aging Neuroscience
Soggetti:
regional white matter hyperintensity volume
hippocampal volume
brain aging
subjective memory complaints
scaled subprofile model
multivariate analyses
Accesso online:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

Accesso online

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full

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