Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging

Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a cohort of 194 healthy older adults ages 50–89, we used...

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Main Authors: Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
格式: Article
語言:English
出版: Frontiers Media S.A. 2024-03-01
叢編:Frontiers in Aging Neuroscience
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1349449/full