Clinically relevant orthotopic xenograft models of patient-derived glioblastoma in zebrafish

Clinically relevant orthotopic xenograft models of patient-derived glioblastoma in zebrafish

An accurate prediction of the intracranial infiltration tendency and drug response of individual glioblastoma (GBM) cells is essential for personalized prognosis and treatment for this disease. However, the clinical utility of mouse patient-derived orthotopic xenograft (PDOX) models remains limited...

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Bibliographic Details
Main Authors: Xiaolin Ai, Zengpanpan Ye, Chaoxin Xiao, Jian Zhong, Joseph J. Lancman, Xuelan Chen, Xiangyu Pan, Yu Yang, Lin Zhou, Xiang Wang, Huashan Shi, Dongmei Zhang, Yuqin Yao, Dan Cao, Chengjian Zhao
Format: Article
Language:English
Published: The Company of Biologists 2022-04-01
Series:Disease Models & Mechanisms
Subjects:
zebrafish
glioblastoma
heterogeneity
blood–brain barrier
pdx
pdox
Online Access:http://dmm.biologists.org/content/15/4/dmm049109

Internet

http://dmm.biologists.org/content/15/4/dmm049109

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