Open and closed states of Candida antarctica lipase B: protonation and the mechanism of interfacial activation1

Lipases (EC 3.1.1.3) are ubiquitous hydrolases for the carboxyl ester bond of water-insoluble substrates, such as triacylglycerols, phospholipids, and other insoluble substrates, acting in aqueous as well as in low-water media, thus being of considerable physiological significance with high interest...

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Bibliographic Details
Main Authors: Benjamin Stauch, Stuart J. Fisher, Michele Cianci
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309536