Cascading effects of hypobaric hypoxia on the testis: insights from a single-cell RNA sequencing analysis

Most mammals tolerate exposure to hypobaric hypoxia poorly as it may affect multiple regulatory mechanisms and inhibit cell proliferation, promote apoptosis, limit tissue vascularization, and disrupt the acid–base equilibrium. Here, we quantified the functional state of germ cell development and dem...

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Bibliographic Details
Main Authors: Yun-Hua Ji, Lin-Meng Wang, Fu-Xun Zhang, Hao-Zhong Hou, Zhi-Rong Luo, Qi Xue, Man-Man Shi, Yong Jiao, Dong Cui, Da-Li He, Wei Xue, Yu-qi Wen, Qi-Sheng Tang, Bo Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1282119/full