Profile-Wise Analysis: A profile likelihood-based workflow for identifiability analysis, estimation, and prediction with mechanistic mathematical models.

Interpreting data using mechanistic mathematical models provides a foundation for discovery and decision-making in all areas of science and engineering. Developing mechanistic insight by combining mathematical models and experimental data is especially critical in mathematical biology as new data an...

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Bibliographic Details
Main Authors: Matthew J Simpson, Oliver J Maclaren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011515&type=printable