Beyond adaptive immunity: induction of trained immunity by COVID-19 adenoviral vaccines

The COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, has resulted in much human suffering and societal disruption. The ChAdOx1 nCoV-19 vaccine against COVID-19 has had a crucial role in the fight against the pandemic. While ChAdOx1 nCoV-19 has been shown to induce adaptive B and T cell respo...

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Bibliographic Details
Main Authors: Mihai G. Netea, Leo A.B. Joosten
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-01-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI166467