Diterpenoid Caesalmin C Delays Aβ-Induced Paralysis Symptoms via the DAF-16 Pathway in <i>Caenorhabditis elegans</i>

Diterpenoid Caesalmin C Delays Aβ-Induced Paralysis Symptoms via the DAF-16 Pathway in <i>Caenorhabditis elegans</i>

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the world. However, there is no effective drug to cure it. Caesalmin C is a cassane-type diterpenoid abundant in <i>Caesalpinia bonduc</i> (Linn.) Roxb. In this study, we investigated the effect of caesalmin C on...

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Bibliographic Details
Main Authors: Zong-Ping Zhang, Xue Bai, Wen-Bo Cui, Xiao-Han Chen, Xu Liu, De-Juan Zhi, Zhan-Xin Zhang, Dong-Qing Fei, Dong-Sheng Wang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
caesalmin C
Alzheimer’s disease
<i>Caenorhabditis elegans</i>
amyloid β-protein
DAF-16
Online Access:https://www.mdpi.com/1422-0067/23/12/6871

Internet

https://www.mdpi.com/1422-0067/23/12/6871

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