Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents

Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents

Numerous reports have shown that conjugated benzimidazole derivatives possess various kinds of biological activities, including anticancer properties. In this report, we designed and synthesized 24 new molecules comprising a benzimidazole ring, arene, and alkyl chain-bearing cyclic moieties. The res...

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Bibliographic Details
Main Authors: Cheng-Ying Hsieh, Pi-Wen Ko, Yu-Jui Chang, Mohit Kapoor, Yu-Chuan Liang, Hsueh-Liang Chu, Hui-Hsien Lin, Jia-Cherng Horng, Ming-Hua Hsu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
anticancer activity
benzimidazole
chalcone
human lung carcinoma
human breast adenocarcinoma
human liver carcinoma
human ovarian carcinoma
Online Access:https://www.mdpi.com/1420-3049/24/18/3259

Internet

https://www.mdpi.com/1420-3049/24/18/3259

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