Mast Cell–Tumor Interactions: Molecular Mechanisms of Recruitment, Intratumoral Communication and Potential Therapeutic Targets for Tumor Growth

Mast Cell–Tumor Interactions: Molecular Mechanisms of Recruitment, Intratumoral Communication and Potential Therapeutic Targets for Tumor Growth

Mast cells (MCs) are tissue-resident immune cells that are important players in diseases associated with chronic inflammation such as cancer. Since MCs can infiltrate solid tumors and promote or limit tumor growth, a possible polarization of MCs to pro-tumoral or anti-tumoral phenotypes has been pro...

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Bibliographic Details
Main Authors: Deisy Segura-Villalobos, Itzel G. Ramírez-Moreno, Magnolia Martínez-Aguilar, Alfredo Ibarra-Sánchez, J. Omar Muñoz-Bello, Isabel Anaya-Rubio, Alejandro Padilla, Marina Macías-Silva, Marcela Lizano, Claudia González-Espinosa
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
mast cells
cancer
signaling pathways
hypoxia
MC polarization
bioactive lipids
Online Access:https://www.mdpi.com/2073-4409/11/3/349

Internet

https://www.mdpi.com/2073-4409/11/3/349

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