Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis

Abstract Ferroptosis, which is characterized by intracellular iron accumulation and lipid peroxidation, is a newly described form of regulated cell death that may play a key role in tumour suppression. In the present study, we investigated the expression profiles and biological effects of fascin act...

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Bibliographic Details
Main Authors: Cong Chen, Bojian Xie, Zhaoqing Li, Lini Chen, Yongxia Chen, Jichun Zhou, Siwei Ju, Yulu Zhou, Xun Zhang, Wenying Zhuo, Jingjing Yang, Misha Mao, Ling Xu, Linbo Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04579-1