Development of a Novel Anti-CD44 Variant 6 Monoclonal Antibody C<sub>44</sub>Mab-9 for Multiple Applications against Colorectal Carcinomas

Development of a Novel Anti-CD44 Variant 6 Monoclonal Antibody C<sub>44</sub>Mab-9 for Multiple Applications against Colorectal Carcinomas

CD44 is a cell surface glycoprotein, and its isoforms are produced by the alternative splicing with the standard and variant exons. The CD44 variant exon-containing isoforms (CD44v) are overexpressed in carcinomas. CD44v6 is one of the CD44v, and its overexpression predicts poor prognosis in colorec...

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Bibliographic Details
Main Authors: Ryo Ejima, Hiroyuki Suzuki, Tomohiro Tanaka, Teizo Asano, Mika K. Kaneko, Yukinari Kato
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
CD44
CD44v6
monoclonal antibody
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/24/4/4007

Internet

https://www.mdpi.com/1422-0067/24/4/4007

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