Paeonol inhibits profibrotic signaling and HOTAIR expression in fibrotic buccal mucosal fibroblasts

Background/purpose: Betel nut chewing is the major risk factor of oral submucous fibrosis (OSF). Various studies have sought to discover alternative strategies to alleviate oral fibrogenesis. In the present study, we aimed to evaluate the anti-fibrosis effect of paeonol, a phenolic component derived...

Full description

Bibliographic Details
Main Authors: Dennis Chun-Yu Ho, Szu-Han Chen, Chih-Yuan Fang, Chang-Wei Hsieh, Pei-Ling Hsieh, Yi-Wen Liao, Cheng-Chia Yu, Lo-Lin Tsai
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664621004733