Cardiovascular Involvement in Pediatric Laminopathies. Report of Six Patients and Literature Revision

Cardiovascular Involvement in Pediatric Laminopathies. Report of Six Patients and Literature Revision

Lamin A/C (LMNA) encodes for two nuclear intermediate filament proteins. Mutations in LMNA cause a highly heterogeneous group of diseases predominantly leading to muscular or cardiac disease, lipodystrophy syndromes, peripheral neuropathy, and accelerated aging disorders. Cardiac involvement include...

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Bibliographic Details
Main Authors: Anwar Baban, Marianna Cicenia, Monia Magliozzi, Maria Gnazzo, Nicoletta Cantarutti, Massimo Stefano Silvetti, Rachele Adorisio, Bruno Dallapiccola, Enrico Bertini, Antonio Novelli, Fabrizio Drago
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pediatrics
Subjects:
LMNA variants
laminopathy
arrhythmias
dilated cardiomyopathy
congenital heart defects
aortic coarctation
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00374/full

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https://www.frontiersin.org/article/10.3389/fped.2020.00374/full

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