SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
Metastatic disease is the major reason for breast cancer-related deaths; therefore, a better understanding of this process and its players is needed. Here the authors report the role of SIRT7 in inhibiting SMAD4-mediated breast cancer metastasis providing a possible therapeutic avenue.
| Main Authors: | , , , , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Nature Portfolio
2017-08-01
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| 叢編: | Nature Communications |
| 在線閱讀: | https://doi.org/10.1038/s41467-017-00396-9 |