Pharmacodynamic material basis and mechanism of Tenghuang Jiangu Wan on osteoarthritis using UPLC-Q-TOF-MS integrated with target network pharmacology

Pharmacodynamic material basis and mechanism of Tenghuang Jiangu Wan on osteoarthritis using UPLC-Q-TOF-MS integrated with target network pharmacology

Tenghuang Jiangu Wan (THJGW) is a commonly utilized treatment for osteoarthritis (OA), yet its pharmacodynamic material basis and molecular mechanism remain inadequately understood. This study systematically characterized the in vitro and in vivo chemical components of THJGW using ultra-performance...

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Bibliographic Details
Main Authors: Dong Xie, Guangfu Lv, Yuchen Wang, Wenjing Zhang, Nian Li, Yao Duan, Qing Huang, Ge Chen, Zifeng Pi, Hao Yue
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Arabian Journal of Chemistry
Subjects:
Tenghuang Jiangu Wan
UPLC-Q-TOF-MS
Osteoarthritis
Pharmacodynamic material basis
Target network pharmacology
Mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535224001138

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http://www.sciencedirect.com/science/article/pii/S1878535224001138

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