Pharmacodynamic material basis and mechanism of Tenghuang Jiangu Wan on osteoarthritis using UPLC-Q-TOF-MS integrated with target network pharmacology
Tenghuang Jiangu Wan (THJGW) is a commonly utilized treatment for osteoarthritis (OA), yet its pharmacodynamic material basis and molecular mechanism remain inadequately understood. This study systematically characterized the in vitro and in vivo chemical components of THJGW using ultra-performance...
Main Authors: | Dong Xie, Guangfu Lv, Yuchen Wang, Wenjing Zhang, Nian Li, Yao Duan, Qing Huang, Ge Chen, Zifeng Pi, Hao Yue |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
|
Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535224001138 |
Similar Items
-
In vivo effect of the Chinese Tenghuang Jiangu Formula on cartilage destruction and subchondral bone sclerosis
by: Shuaijun Li, et al.
Published: (2021-11-01) -
Study on pharmacodynamic material basis and mechanism of anti-inflammatory effect of Tibetan medicine Gentiana lawrencei var. farreri based on UPLC-Q-TOF/MS combined with network pharmacology and molecular docking
by: Jie Zhang, et al.
Published: (2025-01-01) -
Herbal formula xuling-jiangu improves bone metabolic balance in rats with ovariectomy-induced osteoporosis via the gut-bone axis
by: Juan Chen, et al.
Published: (2024-11-01) -
The therapeutic mechanism of Compound Lurong Jiangu Capsule for the treatment of cadmium-induced osteoporosis: network pharmacology and experimental verification
by: Ya-shuang Zhou, et al.
Published: (2024-07-01) -
Analysis of Chemical Constituents in Wuzi-Yanzong-Wan by UPLC-ESI-LTQ-Orbitrap-MS
by: Dixin Zou, et al.
Published: (2015-12-01)