HSV-1/TLR9-Mediated IFNβ and TNFα Induction Is Mal-Dependent in Macrophages
Innate immune response is a universal mechanism against invading pathogens. Toll-like receptors (TLRs), being part of a first line of defense, are responsible for detecting a variety of microorganisms. Among them TLR9, which is localized in endosomes, acts as a sensor for unmethylated CpG motifs pre...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2019-12-01
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| Series: | Journal of Innate Immunity |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/504542 |