Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.

Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.

Osteoporosis is a silent disease, characterized by a porous bone micro-structure that enhances risk for fractures and associated disabilities. Senile, or age-related osteoporosis (SO), affects both men and women, resulting in increased morbidity and mortality. However, cellular and molecular mechani...

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Bibliographic Details
Main Authors: Ramaswamy Sharma, Danielle Callaway, Difernando Vanegas, Michelle Bendele, Marisa Lopez-Cruzan, Diane Horn, Teja Guda, Roberto Fajardo, Sherry Abboud-Werner, Brian Herman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972236?pdf=render

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http://europepmc.org/articles/PMC3972236?pdf=render

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