Inhibitor of bromodomain and extraterminal domain proteins decreases transcription of Cd33 in the brain of mice subjected to systemic inflammation; a promising strategy for neuroprotection

Inhibitor of bromodomain and extraterminal domain proteins decreases transcription of Cd33 in the brain of mice subjected to systemic inflammation; a promising strategy for neuroprotection

The neuroinflammation is a crucial component of virtually all neurodegenerative disorders, including Alzheimer’s disease (AD). The bacterial lipopolysaccharide (LPS), a potent activator of the innate immune system, was suggested to influence or even trigger the neuropathological alterations in AD. L...

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Bibliographic Details
Main Authors: Grzegorz A. Czapski, Marta Matuszewska, Magdalena Cieślik, Joanna B. Strosznajder
Format: Article
Language:English
Published: Termedia Publishing House 2024-05-01
Series:Folia Neuropathologica
Subjects:
alzheimer’s disease
systemic inflammatory response
endotoxin
bromodomain and extraterminal domain proteins
hippocampus
microglia
Online Access:https://www.termedia.pl/Inhibitor-of-bromodomain-and-extraterminal-domain-proteins-decreases-transcription-of-Cd33-in-the-brain-of-mice-subjected-to-systemic-inflammation-a-promising-strategy-r-nfor-neuroprotection,20,53626,1,1.html

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https://www.termedia.pl/Inhibitor-of-bromodomain-and-extraterminal-domain-proteins-decreases-transcription-of-Cd33-in-the-brain-of-mice-subjected-to-systemic-inflammation-a-promising-strategy-r-nfor-neuroprotection,20,53626,1,1.html

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