Establishment of the multi-component bone-on-a-chip: to explore therapeutic potential of DNA aptamers on endothelial cells

Establishment of the multi-component bone-on-a-chip: to explore therapeutic potential of DNA aptamers on endothelial cells

Background: Despite great efforts to develop microvascular bone chips in previous studies, current bone chips still lacked multi-component of human-derived cells close to human bone tissue. Bone microvascular endothelial cells (BMECs) were demonstrated to be closely related to the glucocorticoid (GC...

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Bibliographic Details
Main Authors: Xiaoyu Fan, Yuhan Yan, Lianhui Zhao, Xin Xu, Yiyang Dong, Wei Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
bone-on-a-chip
microfluidic system
osteonecrosis of the femoral head
aptamer
multi-component
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1183163/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1183163/full

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