Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

Abstract Background Repetitive elements are now known to have relevant cellular functions, including self-complementary sequences that form double stranded (ds) RNA. There are numerous pathways that determine the fate of endogenous dsRNA, and misregulation of endogenous dsRNA is a driver of autoimmu...

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Bibliographic Details
Main Authors: Wilson H. McKerrow, Yiannis A. Savva, Ali Rezaei, Robert A. Reenan, Charles E. Lawrence
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Genomics
Subjects:
RNA editing
Hyper-editing
Alignment
Repetitive element
Transposable element
dsRNA
Online Access:http://link.springer.com/article/10.1186/s12864-017-3898-9

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http://link.springer.com/article/10.1186/s12864-017-3898-9

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