Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences

Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences

The ability to genetically encode non-natural amino acids (nnAAs) into proteins offers an expanded tool set for protein engineering. nnAAs containing unique functional moieties have enabled the study of post-translational modifications, protein interactions, and protein folding. In addition, nnAAs h...

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Bibliographic Details
Main Authors: Gargi Roy, Jason Reier, Andrew Garcia, Tom Martin, Megan Rice, Jihong Wang, Meagan Prophet, Ronald Christie, William Dall’Acqua, Sanjeev Ahuja, Michael A Bowen, Marcello Marelli
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:mAbs
Subjects:
Antibody drug conjugate
IgG
non-natural amino acid
PylRS
tRNA
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2019.1684749

Internet

https://www.tandfonline.com/doi/10.1080/19420862.2019.1684749

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