Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys1

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys1

Accumulation of cholesterol in arterial macrophages may contribute to diabetes-accelerated atherosclerotic cardiovascular disease. The ATP-binding cassette transporter ABCA1 is a cardioprotective membrane protein that mediates cholesterol export from macrophages. Factors elevated in diabetes, such a...

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Bibliographic Details
Main Authors: Chongren Tang, Jenny E. Kanter, Karin E. Bornfeldt, Renee C. Leboeuf, John F. Oram
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
ATP-binding cassette transporter A1
cardiovascular disease
liver
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370942

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http://www.sciencedirect.com/science/article/pii/S0022227520370942

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