Intrahepatic activated leukocyte cell adhesion molecule induces CD6highCD4+ T cell infiltration in autoimmune hepatitis

Intrahepatic activated leukocyte cell adhesion molecule induces CD6highCD4+ T cell infiltration in autoimmune hepatitis

Background and objectivesAutoimmune hepatitis (AIH) is characterized by the expansion and accumulation of pathogenic T cells in liver. Although CD6 and its ligand activated leukocyte cell adhesion molecule (ALCAM) are involved in the evolution of multiple inflammatory diseases, their roles in the pa...

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Bibliographic Details
Main Authors: Qiwei Qian, Nana Cui, Bingyuan Huang, Yudong Zhao, Qiaoyan Liu, Mingli Hu, Bo Li, Qixia Wang, Qi Miao, Zhengrui You, Xiong Ma, Ruqi Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
autoimmune hepatitis
activated leukocyte cell adhesion molecule
CD6
migration
immune regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.967944/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.967944/full

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