Efficient production of 2′-fucosyllactose from fructose through metabolically engineered recombinant Escherichia coli

Efficient production of 2′-fucosyllactose from fructose through metabolically engineered recombinant Escherichia coli

Abstract Background The biosynthesis of human milk oligosaccharides (HMOs) using several microbial systems has garnered considerable interest for their value in pharmaceutics and food industries. 2′-Fucosyllactose (2′-FL), the most abundant oligosaccharide in HMOs, is usually produced using chemical...

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Bibliographic Details
Main Authors: Ran You, Lei Wang, Meirong Hu, Yong Tao
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Microbial Cell Factories
Subjects:
Metabolic engineering
Escherichia coli
2′-Fucosyllactose
High stoichiometric yield
Fed-batch bioconversion
Online Access:https://doi.org/10.1186/s12934-024-02312-5

Internet

https://doi.org/10.1186/s12934-024-02312-5

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