Influence of traumatic brain injury on extracellular tau elimination at the blood–brain barrier

Abstract Repetitive head trauma has been associated with the accumulation of tau species in the brain. Our prior work showed brain vascular mural cells contribute to tau processing in the brain, and that these cells progressively degenerate following repetitive mild traumatic brain injury (r-mTBI)....

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Bibliographic Details
Main Authors: Maxwell Eisenbaum, Andrew Pearson, Arissa Gratkowski, Benoit Mouzon, Michael Mullan, Fiona Crawford, Joseph Ojo, Corbin Bachmeier
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-021-00283-y