Neutral Lipids Are Not a Source of Arachidonic Acid for Lipid Mediator Signaling in Human Foamy Monocytes

Neutral Lipids Are Not a Source of Arachidonic Acid for Lipid Mediator Signaling in Human Foamy Monocytes

Human monocytes exposed to free arachidonic acid (AA), a secretory product of endothelial cells, acquire a foamy phenotype which is due to the accumulation of cytoplasmic lipid droplets with high AA content. Recruitment of foamy monocytes to the inflamed endothelium contributes to the development of...

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Bibliographic Details
Main Authors: Carlos Guijas, Miguel A. Bermúdez, Clara Meana, Alma M. Astudillo, Laura Pereira, Lidia Fernández-Caballero, María A. Balboa, Jesús Balsinde
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
arachidonic acid
mass spectrometry
lipid signaling
inflammation
phospholipase A<sub>2</sub>
monocytes/macrophages
Online Access:https://www.mdpi.com/2073-4409/8/8/941

Internet

https://www.mdpi.com/2073-4409/8/8/941

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