Cell Type-Specific p38δ Targeting Reveals a Context-, Stage-, and Sex-Dependent Regulation of Skin Carcinogenesis

Cell Type-Specific p38δ Targeting Reveals a Context-, Stage-, and Sex-Dependent Regulation of Skin Carcinogenesis

Activation and/or upregulated expression of p38δ are demonstrated in human skin malignancies including cutaneous squamous cell carcinoma, suggesting a role for p38δ in skin carcinogenesis. We previously reported that mice with germline deletion of the p38δ gene are signifi...

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Bibliographic Details
Main Authors: Alexi Kiss, Aaron C. Koppel, Emily Murphy, Maxwell Sall, Meral Barlas, Grace Kissling, Tatiana Efimova
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
p38δ/MAPK13
skin carcinogenesis
conditional knockout mice
keratinocytes
myeloid cells
Online Access:https://www.mdpi.com/1422-0067/20/7/1532

Internet

https://www.mdpi.com/1422-0067/20/7/1532

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