Exploring novel Apalutamide analogues as potential therapeutics for prostate cancer: design, molecular docking investigations and molecular dynamics simulation

Introduction: Prostate cancer (PC) ranks as the second most frequent type of cancer in men and is the fourth largest cause of mortality worldwide. Androgenic hormones such as testosterone and dihydrotestosterone are crucial for the development and progression of the prostate gland. Androgenic hormon...

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Bibliographic Details
Main Authors: Ajay Kumar Gupta, Yogesh Vaishnav, Sanmati Kumar Jain, Sivakumar Annadurai, Neeraj Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1418975/full