Trypanosoma cruzi disrupts thymic homeostasis by altering intrathymic and systemic stress-related endocrine circuitries.

Trypanosoma cruzi disrupts thymic homeostasis by altering intrathymic and systemic stress-related endocrine circuitries.

We have previously shown that experimental infection caused by Trypanosoma cruzi is associated with changes in the hypothalamus-pituitary-adrenal axis. Increased glucocorticoid (GC) levels are believed to be protective against the effects of acute stress during infection but result in depletion of C...

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Bibliographic Details
Main Authors: Ailin Lepletier, Vinicius Frias de Carvalho, Patricia Machado Rodrigues e Silva, Silvina Villar, Ana Rosa Pérez, Wilson Savino, Alexandre Morrot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3852165?pdf=render

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http://europepmc.org/articles/PMC3852165?pdf=render

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