Total Syntheses of the Proposed Structure of Iriomoteolide-1a, -1b and Synthesis of Three Derivatives for Structural Studies

Iriomoteolide-1a and iriomoteolide-1b are very potent cytotoxic agents, isolated from marine dinoflagellates. We carried out the enantioselective syntheses of the proposed structures of these natural products. However, our analysis of the NMR spectra of the synthetic iriomoteolide-1a and the natural...

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Bibliographic Details
Main Authors: Arun K. Ghosh, Hao Yuan
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/20/10/587