RIPpore: A Novel Host-Derived Method for the Identification of Ricin Intoxication through Oxford Nanopore Direct RNA Sequencing

Ricin is a toxin which enters cells and depurinates an adenine base in the sarcin-ricin loop in the large ribosomal subunit, leading to the inhibition of protein translation and cell death. We postulated that this depurination event could be detected using Oxford Nanopore Technologies (ONT) direct R...

全面介绍

书目详细资料
Main Authors: Yan Ryan, Abbie Harrison, Hannah Trivett, Catherine Hartley, Jonathan David, Graeme C. Clark, Julian A. Hiscox
格式: 文件
语言:English
出版: MDPI AG 2022-07-01
丛编:Toxins
主题:
在线阅读:https://www.mdpi.com/2072-6651/14/7/470