Menstrual blood derived mesenchymal stem cells combined with Bushen Tiaochong recipe improved chemotherapy-induced premature ovarian failure in mice by inhibiting GADD45b expression in the cell cycle pathway

Menstrual blood derived mesenchymal stem cells combined with Bushen Tiaochong recipe improved chemotherapy-induced premature ovarian failure in mice by inhibiting GADD45b expression in the cell cycle pathway

Abstract Background To investigate the therapeutic effects of menstrual blood derived mesenchymal stem cells (MB-MSCs) combined with Bushen Tiaochong recipe (BSTCR) on epirubicin induced premature ovarian failure (POF) in mice. Methods Twenty-four female C57BL/6 mice of 6–8 weeks were intraperitonea...

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Bibliographic Details
Main Authors: Fengyi Guo, Tian Xia, Yedan Zhang, Xiaotong Ma, Zhongrui Yan, Shaohua Hao, Yali Han, Ruihong Ma, Yuan Zhou, Xue Du
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Mesenchymal stem cells
Menstrual blood
Bushen Tiaochong recipe
Premature ovarian failure
Epirubicin
GADD45
Online Access:http://link.springer.com/article/10.1186/s12958-019-0499-2

Internet

http://link.springer.com/article/10.1186/s12958-019-0499-2

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