Synthesis of compounds related to the anti-migraine drug eletriptan hydrobromide

Eletriptan hydrobromide (1) is a selective serotonin (5-HT1) agonist, used for the acute treatment of the headache phase of migraine attacks. During the manufacture of eletriptan hydrobromide the formation of various impurities were observed and identified by LC–MS. To control the formation of these...

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Bibliographic Details
Main Authors: Suri Babu Madasu, Nagaji Ambabhai Vekariya, M. N. V. D. Hari Kiran, Badarinadh Gupta, Aminul Islam, Paul S. Douglas, Korupolu Raghu Babu
Format: Article
Language:English
Published: Beilstein-Institut 2012-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.162