Mystery of fatal ‘staggering disease’ unravelled: novel rustrela virus causes severe meningoencephalomyelitis in domestic cats

Rustrela virus (RusV) was detected in the brains of 27 out of 29 domestic cats with ‘staggering disease’, but not of 29 control cats. This suggests RusV as the long-sought causative agent of ‘staggering disease’, which had been obscure for 50 years.

Bibliographic Details
Main Authors: Kaspar Matiasek, Florian Pfaff, Herbert Weissenböck, Claudia Wylezich, Jolanta Kolodziejek, Sofia Tengstrand, Frauke Ecke, Sina Nippert, Philip Starcky, Benedikt Litz, Jasmin Nessler, Peter Wohlsein, Christina Baumbach, Lars Mundhenk, Andrea Aebischer, Sven Reiche, Pia Weidinger, Karin M. Olofsson, Cecilia Rohdin, Christiane Weissenbacher-Lang, Julia Matt, Marco Rosati, Thomas Flegel, Birger Hörnfeldt, Dirk Höper, Rainer G. Ulrich, Norbert Nowotny, Martin Beer, Cecilia Ley, Dennis Rubbenstroth
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36204-w