Different Neutralization Profiles After Primary SARS-CoV-2 Omicron BA.1 and BA.2 Infections

Different Neutralization Profiles After Primary SARS-CoV-2 Omicron BA.1 and BA.2 Infections

Background and MethodsThe SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) Omicron (B.1.1.529) variant is the antigenically most distinct variant to date. As the heavily mutated spike protein enables neutralization escape, we studied serum-neutralizing activities of naïve and vaccinated...

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Bibliographic Details
Main Authors: Iris Medits, David N. Springer, Marianne Graninger, Jeremy V. Camp, Eva Höltl, Stephan W. Aberle, Marianna T. Traugott, Wolfgang Hoepler, Josef Deutsch, Oliver Lammel, Christian Borsodi, Elisabeth Puchhammer-Stöckl, Alexander Zoufaly, Lukas Weseslindtner, Judith H. Aberle, Karin Stiasny
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
SARS-CoV-2 variant of concern
Omicron sub-lineages
SARS-CoV-2 neutralization
immune escape
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.946318/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.946318/full

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