White matter microstructural integrity mediates associations between prenatal endocrine-disrupting chemicals exposure and intelligence in adolescents

White matter microstructural integrity mediates associations between prenatal endocrine-disrupting chemicals exposure and intelligence in adolescents

Per- and polyfluoroalkyl substances (PFAS) and phthalic acid esters (PAEs) are well-known endocrine-disrupting chemicals (EDCs) that potentially affect child neurodevelopment. We aimed to investigate the effects of prenatal exposure to PFAS and PAEs on macro- and micro-structural brain development a...

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Bibliographic Details
Main Authors: Shi-Ming Wang, Hui-Ju Wen, Fan Huang, Chien-Wen Sun, Chih-Mao Huang, Shu-Li Wang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
Phthalic acid esters (PAE)
Perfluoroalkyl substances (PFAS)
Diffusion tensor imaging (DTI)
Diffusion kurtosis imaging (DKI) and Neurite orientation dispersion and density imaging (NODDI)
Intelligence quotient (IQ)
Mediation analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000282

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http://www.sciencedirect.com/science/article/pii/S2213158225000282

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