Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism

Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism

Parkinson's disease (PD) is a neurodegenerative movement disorder, which affects approximately 1–2% of the population over 60 years of age. Current treatments for PD are symptomatic, and the pathology of the disease continues to progresses over time until palliative care is required. Mitochondr...

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Detaylı Bibliyografya
Asıl Yazarlar: Jacqueline A. Gleave, Lindsay R. Arathoon, Dennison Trinh, Kristin E. Lizal, Nicolas Giguère, James H.M. Barber, Zainab Najarali, M. Hassan Khan, Sherri L. Thiele, Mahin S. Semmen, James B. Koprich, Jonathan M. Brotchie, James H. Eubanks, Louis-Eric Trudeau, Joanne E. Nash
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2017-10-01
Seri Bilgileri:Neurobiology of Disease
Konular:
Parkinson's disease
Virally over-expressing mutant α-synuclein rat
Neuroprotection
Substantia nigra
Mitochondria
Sirtuin 3
Online Erişim:http://www.sciencedirect.com/science/article/pii/S0969996117301365

Internet

http://www.sciencedirect.com/science/article/pii/S0969996117301365

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