Characterization of the Basal and mTOR-Dependent Acute Pulmonary and Systemic Immune Response in a Murine Model of Combined Burn and Inhalation Injury

Characterization of the Basal and mTOR-Dependent Acute Pulmonary and Systemic Immune Response in a Murine Model of Combined Burn and Inhalation Injury

Severe burn injury leads to a cascade of local and systemic immune responses that trigger an extreme state of immune dysfunction, leaving the patient highly susceptible to acute and chronic infection. When combined with inhalation injury, burn patients have higher mortality and a greater chance of d...

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Bibliographic Details
Main Authors: Hannah R. Hall, Cressida Mahung, Julia L. M. Dunn, Laurel M. Kartchner, Roland F. Seim, Bruce A. Cairns, Shannon M. Wallet, Robert Maile
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
burn injury
inhalation injury
mTOR
Online Access:https://www.mdpi.com/1422-0067/23/15/8779

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https://www.mdpi.com/1422-0067/23/15/8779

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