Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual diseaseResearch in context

Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual diseaseResearch in context

Summary: Background: Liquid biopsy is a promising non-invasive alternative for cancer screening and minimal residual disease (MRD) detection, although there are some concerns regarding its clinical applications. We aimed to develop an accurate detection platform based on liquid biopsy for both canc...

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Bibliographic Details
Main Authors: Yun Li, Guanchao Jiang, Wendy Wu, Hao Yang, Yichen Jin, Manqi Wu, Wenjie Liu, Airong Yang, Olga Chervova, Sujie Zhang, Lu Zheng, Xueying Zhang, Fengxia Du, Nnennaya Kanu, Lin Wu, Fan Yang, Jun Wang, Kezhong Chen
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:EBioMedicine
Subjects:
Liquid biopsy
Whole-genome sequencing
Lung cancer
Diagnostic model
Prognostic model
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001184

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http://www.sciencedirect.com/science/article/pii/S2352396423001184

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