VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity

VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity

Inflammatory bowel diseases (IBD) are chronic intestinal disorders that result from an inappropriate inflammatory response to the microbiota in genetically susceptible individuals, often triggered by environmental stressors. Part of this response is the persistent inflammation and tissue injury asso...

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Bibliographic Details
Main Authors: Josie Ward, Suisheng Zhang, Adam Sikora, Radoslaw Michalski, Yuting Yin, Aurora D'Alessio, Rachel M. McLoughlin, Vincent Jaquet, Franck Fieschi, Ulla G. Knaus
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Redox Biology
Subjects:
NADPH oxidase
NOX
DUOX
NOX1 model
Peroxynitrite
Inflammatory bowel disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003063

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http://www.sciencedirect.com/science/article/pii/S2213231723003063

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