Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection

Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection

For the past several years, fundamental research on Sigma-1R (S1R) protein has unveiled its necessity for maintaining proper cellular homeostasis through modulation of calcium and lipid exchange between the endoplasmic reticulum (ER) and mitochondria, ER-stress response, and many other mechanisms. M...

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Bibliographic Details
Main Authors: Véronik Lachance, Sara-Maude Bélanger, Célia Hay, Victoria Le Corvec, Vina Banouvong, Mathieu Lapalme, Khadija Tarmoun, Guillaume Beaucaire, Marc P. Lussier, Saïd Kourrich
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Sigma-1R
chaperone
calcium
lipid
homeostasis
endoplasmic reticulum
Online Access:https://www.mdpi.com/1422-0067/24/3/1971

Internet

https://www.mdpi.com/1422-0067/24/3/1971

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