Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage colon carcinogenesis

Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage colon carcinogenesis

The enhanced chemopreventive action against 1,2 Dimethylhydrazine (DMH)-induced preneoplastic lesion in rats could be achieved via simultaneous administration of the antidepressant fluoxetine (FLX) with two natural polyphenolic compounds viz., kaempferol (KMP) and/or epigallocatechin-gallate (EGCG)....

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Bibliographic Details
Main Authors: Eman S.G. Hassan, Nahed M. Hassanein, Helmy M. Sayed Ahmed
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Pharmacological Sciences
Subjects:
1,2 Dimethylhydrazine
Epigallocatechin gallate
Kaempferol
Fluoxetine
Colon cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320301031

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http://www.sciencedirect.com/science/article/pii/S1347861320301031

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