Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness
Abstract Background Chromosome is one of the most fundamental part of cell biology where DNA holds the hierarchical information. DNA compacts its size by forming loops, and these regions house various protein particles, including CTCF, SMC3, H3 histone. Numerous sequencing methods, such as Hi-C, ChI...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-024-05713-w |