Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness

Abstract Background Chromosome is one of the most fundamental part of cell biology where DNA holds the hierarchical information. DNA compacts its size by forming loops, and these regions house various protein particles, including CTCF, SMC3, H3 histone. Numerous sequencing methods, such as Hi-C, ChI...

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Bibliographic Details
Main Authors: H. M. A. Mohit Chowdhury, Terrance Boult, Oluwatosin Oluwadare
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-024-05713-w