Protein complexes detection based on node local properties and gene expression in PPI weighted networks

Abstract Background Identifying protein complexes from protein–protein interaction (PPI) networks is a crucial task, and many related algorithms have been developed. Most algorithms usually employ direct neighbors of nodes and ignore resource allocation and second-order neighbors. The effective use...

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Bibliographic Details
Main Authors: Yang Yu, Dezhou Kong
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04543-4